Please use this identifier to cite or link to this item: http://repository.i3l.ac.id/jspui/handle/123456789/520
Full metadata record
DC FieldValueLanguage
dc.contributor.authorWirya, Jason-
dc.date.accessioned2022-06-23T02:26:56Z-
dc.date.available2022-06-23T02:26:56Z-
dc.date.issued2020-10-02-
dc.identifier.urihttp://repository.i3l.ac.id/jspui/handle/123456789/520-
dc.description.abstractDengue virus is a mosquito-borne viral disease that major health concern in the tropics such as Indonesia, being one of the largest dengue-endemic countries in the world. Pasuruan, despite being among the most vulnerable regions in East Java, lacked molecular data about the virus, making monitoring the dynamics of the virus impossible. The objective of this study is to investigate which antigenically distinct serotypes and genotypes are predominant in Pasuruan. 50 blood samples were obtained from dengue-suspected patients from at from Regional General Hospital dr. R. Soedarsono between May and July 2019. Serotyping was performed using RT and multiplex PCR. Genotyping was performed by constructing a phylogenetic tree using the NJ method. 7 out of 50 samples were successfully isolated (14% isolation rate). All 7 samples are identified as DENV-4. 1 out of the 7 samples were successfully sequenced. The phylogenetic tree suggests that the sequenced sample is DENV-4 Genotype II. The results of this study provide more molecular data of dengue virus for further investigation of the viral dynamics in Pasuruan.en_US
dc.language.isoenen_US
dc.publisherIndonesia International Institute for Life Sciencesen_US
dc.relation.ispartofseriesBM 20-011;T202010031-
dc.subjectDengue Virusen_US
dc.subjectSerotypeen_US
dc.subjectGenotypeen_US
dc.subjectPasuruanen_US
dc.subjectEast Javaen_US
dc.titleMolecular Study of Dengue Virus in Pasuruan East Java, Indonesiaen_US
dc.typeThesisen_US
Appears in Collections:Biomedicine

Files in This Item:
File Description SizeFormat 
T202012018_BM_Jason Wirya_16010048.pdf
  Restricted Access
Full text1.63 MBAdobe PDFView/Open Request a copy
Cover.pdfCover58.26 kBAdobe PDFView/Open
Abstract.pdfAbstract212.38 kBAdobe PDFView/Open
Chapter 1.pdfChapter 1216.44 kBAdobe PDFView/Open
References.pdfReferences243.12 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.