Role of Fatty Acid Synthesis Towards HCV Replication See

Hepatitis C Virus (HCV) remains a significant global health threat, contributing to chronic infections and hepatic complications, including hepatic steatosis and hepatocellular carcinoma (HCC). This study investigates the intricate relationship between HCV and fatty acid metabolism, focusing on lipid droplet accumulation and the impact of HCV on fatty acid synthesis genes. Utilizing an HCV-infected hepatocyte cell line, observations reveal a substantial increase in lipid droplets induced by H...

Screening Of Potential Compound For Psoriasis Drug Development: Cell-based Study See

Psoriasis is the most common type of chronic inflammatory skin disease clinically characterized by a scaly erythematous eruption in the epidermal skin, primarily caused by the interaction of immune cells and keratinocytes that induces inflammatory skin response. Psoriasis is best characterized as a complex, multifactorial disorder, where both genetic and environmental factors play crucial roles. Current first-in-line topical therapies for psoriasis are costly and ineffective, highlighting the...

In Vitro Investigation Of Antibacterial Properties In Deodorant "x" Against Staphylococcus Epidermidis And Micrococcus Luteus See

The body odor issue has prompted increasing concern among individuals, attributed to the malodorous byproducts of sweat gland activity, particularly in the axillary skin region, which is metabolized by the cutaneous microflora. To address this matter, the formulation of deodorant products has emerged as a potential solution. Comprising a spectrum of compounds and a natural product, reported as “Extract X,” recognized for their antimicrobial properties, these formulations hold promise in mitig...

The Effect Of Drug Dx23 Towards Enhancing Neutrophil Function And Regulating Immune Response See

Neutrophils are the main cells that play a significant role in the innate immune system. Upon a pathogenic invasion, these cells are recruited to the site of infection and perform many different functions. Targeting the neutrophils for therapeutic interventions has been a great challenge due to the complexity of their signaling pathway and mechanisms. Therefore, the search for drug candidates that enhance neutrophil function remains questionable. DX23 is a type of CFTR potentiator originally ...

The Enhancing Effect Of Drug Da-22 On The Immune Response Of Human Neutrophils See

Neutrophils are polymorphonuclear and phagocytic leukocytes that act as the first line of innate immune defense to protect and rapidly kill the invading pathogens from the human body. In general, neutrophils are essential immune cells that play a significant role in the early response to infections through their ability to migrate into affected tissues upon pathogens invasion. The activation of neutrophils contribute significantly to enhancing the immune system’s response by several mechanism...

Determination Of Color Stability On Pet Packaged Fruit Tea Passion Fruit At Pt Sinar Sosro See

PT Sinar Sosro is the world's first company that develops ready-to-drink beverages in packed bottles. The company's primary activity is to manufacture and distribute RTD beverages, mostly tea-based products, to both the domestic and foreign markets. Tea is one of a few plantation commodities that is a mainstay of Indonesia's global market. One of the most important factors to consider while making a great tea beverage is keeping its appearance. Polyethylene terephthalate is colorless and clea...

PRODUCTION PROCESS OF SOHUN AT PANDUS FOOD INDUSTRY See

Pandus Food Industry is an individual company located in Purbalingga, Central Java. The company was founded in 1977. The products provided by Pandus Food Industry are two types of noodle, (1) Sohun and (2) Egg noodles. My position during the internship was to work in the production part as a productive team, learning the production process of Sohun in detail. The objective of internship is to know basic information about sohun and the production process of sohun, fully understand the producti...

Exploring the Physical and Molecular Functions of Rrm2b Gene in Mice as a Possible Treatment for Sarcopenia See

Sarcopenia, an age-related disease where loss of muscle and strength progresses, has become a research interest for scientists over the past few decades. Sarcopenia in and of itself can cause physical incapacity, functional impairment, and even death to patients. Research has shown that mitochondrial dysfunction has been known to cause sarcopenic muscle tissue damage. Furthermore, recent studies have found that the Rrm2b gene may have a correlation with the mitochondrial homeostasis in skelet...

Isolation of Methicillin-Resistant Staphylococcus aureus from Eczema Patient Skin and Its Susceptibility Towards Houttuynia Cordata and Rhodomyrtus Tomentosa See

Staphylococcus aureus (SA) is an opportunistic human pathogen that can cause infections in humans, including atopic dermatitis, also known as eczema. Eczema is a skin condition where patients experience flare-ups characterized by redness, itchiness, dried skin, and may vary among individuals. Interestingly, there is a common pattern where all eczema patients' skin is colonized by SA, and treatment that reduces its colonization could alleviate the patients' symptoms. However, since the discove...