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DC Field | Value | Language |
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dc.contributor.author | Wijaya, Evelyn Jeanette | - |
dc.date.accessioned | 2022-04-14T08:32:25Z | - |
dc.date.available | 2022-04-14T08:32:25Z | - |
dc.date.issued | 2021-12-07 | - |
dc.identifier.uri | http://repository.i3l.ac.id/jspui/handle/123456789/323 | - |
dc.description.abstract | Bacterial cellulose (BC) is a gel matrix substance made of various gram negative bacteria in a sugar rich environment, and has been used in many pharmaceutical and medical industries. One of the functions of BC is as a wound dressing, which according to some studies, BC has a potential to make wound healing more efficient. Due to this reason, this research aims to evaluate the wound healing and antimicrobial properties of BC that has been injected with a probiotics (B.subtilis). The research was done by using 8 male mice that were treated with 3 different treatments, which are BC B.subtilis, BCO (BC Only), and negative control (Gauze). After the wound is observed for a specific amount of time, the tissue is extracted, embedded, sectioned, stained using hematoxylin and eosin, and observed using a light microscope. The BC B.subtilis showed a significant wound size reduction compared to BCO and negative control (p<0.05). However, there is no significant wound size reduction between BCO and negative control (p>0.05). In addition to that, BC B.subtilis showed a more prominent re-epithelialization, which can be concluded that BC has a potential to be used as a wound dressing, as it increase the wound healing rate, and the addition of probiotics are recommended to increase the wound healing even further. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Indonesia International Institute for Life Sciences | en_US |
dc.relation.ispartofseries | Intern2021;PHA | - |
dc.subject | Bacterial Cellulose | en_US |
dc.subject | probiotics | en_US |
dc.subject | negative control | en_US |
dc.subject | BC B.subtilis | en_US |
dc.title | Evaluation of Wound Healing and Antimicrobial Properties of Bacterial Cellulose Containing B.subtilis Cells | en_US |
dc.type | Working Paper | en_US |
Appears in Collections: | Pharmacy |
Files in This Item:
File | Description | Size | Format | |
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intern2021_PHA_Evelyn Jeanette.pdf Restricted Access | 4.14 MB | Adobe PDF | View/Open Request a copy |
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